Recombinant human APLF protein

品牌

Solarbio

编号

P04929

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货号	品牌	纯度/规格	包装	目录价	您的价格
P04929-100ug	Solarbio	100ug	1EA	¥1800.00	¥1800.00
P04929-10ug	Solarbio	10ug	1EA	¥560.00	¥560.00
P04929-1mg	Solarbio	1mg	1EA	¥11200.00	¥11200.00
P04929-50ug	Solarbio	50ug	1EA	¥1120.00	¥1120.00

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中文名称

Recombinant human APLF protein

英文名称

aprataxin and PNKP like factor

内容

产品简介

基因名	APLF
英文全称	aprataxin and PNKP like factor
别称	C2orf13, PALF, XIP1
中文名称	Aprataxin和PNKP样因子
Uniprot	Q8IW19
GeneID	200558
交叉反应(推测)	Human Mouse (Bovine)
氨基酸大小	38kDa
表达氨基酸	1-350aa
Background	Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. Together with PARP3, promotes the retention of the LIG4-XRCC4 complex on chromatin and accelerate DNA ligation during non-homologous end-joining (NHEJ).
Application	Immunology research
Derived from	E.coli
Purification	NI-NTA affinity purification
Formulation	Lyophilized from a 0.2 μm filtered solution of Urea, Tris-HCl, PH8.0.
Shipping	The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage	Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years.
Reconstitution	Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity	Purity≥85% as determined by reducing SDS-PAGE.
Endotoxin	/
规格	10ug ; 50ug ; 100ug ; 1mg
Bioactive	Not tested.
Tag information	With a 6His tag at the N-terminus.
单位	支

以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。

These protocols are for reference only. Solarbio does not independently validate these methods.